Quad Screen: Detection Rate: 75%. False Positive: 5%
for Down syndrome

Quad Screen | Fß

The Quad Screen | Fß is performed in the second trimester of pregnancy, between 15 weeks and 21 weeks, 6 days gestation. The mother's serum is collected and sent to Eurofins NTD, LLC. for analysis. This test analyzes 4 biomarkers found in the mother's serum - alpha-fetoprotein (AFP), free beta human chorionic gonadotrophin (hCG), unconjugated estriol, and inhibin-A. This test is essentially the same as Part 2 of the Sequential Screen | Fß. This test is suggested for patients who present too late in their pregnancy to receive first trimester screening.

The Quad Screen | Fß detects 75% of Down syndrome cases at a 5% false positive rate, and detects 75% of trisomy 18 cases at a 0.3% false positive rate. This test detects 90% of cases of open spina bifida and 98% of cases of anencephaly.

(References 29,30,31)


DISCLAIMER: Pursuant to applicable federal and/or state laboratory requirements, Eurofins NTD, LLC has established and verified the accuracy and precision of its testing services. Tests are developed and performance characteristics determined by Eurofins NTD, LLC. The methods and performance characteristics have been reviewed and approved by the New York State Department of Health.